MedCalc - User-friendly statistical software

News and updates

August 17, 2017

Added chi-square test in Multiple frequency tables.

July 24, 2017

Added the Hodges-Lehmann location estimator in the results section of the Signed rank test, and the Hodges-Lehmann median difference in the results section of the Mann-Whitney test and Wilcoxon test.

Added geometric and harmonic mean as options in Summary statistics and Summary statistics table.

June 2, 2017

Added confidence interval estimation (using bootstrapping) in Age-related reference interval.

Added sample size calculation for regression-based reference limits.

MedCalc spreadsheet has been reconfigured to contain a fixed number of 16384 columns and 1048576 rows.

May 1, 2017

Added sample size calculation for paired samples t-test

Added sample size calculation for confidence intervals.

April 16, 2017

Added "Root mean square" and "Logarithmic" methods for the calculation of the Coefficient of variation from duplicate measurements.

Added "Save differences" option in results window of Paired samples t-test and "Save residuals" option in results window of the Independent samples t-test.

Added test for Normal distribution of data in Normal plot

Added test for Normal distribution of differences in Paired samples t-test.

Added test for Normal distribution of residuals in Independent samples t-test, Regression, Multiple regression, One-way analysis of variance, Two-way analysis of variance, and Analysis of covariance.

April 3, 2017

New: sample size calculation for Bland-Altman plot.

New: option to draw lines for the Maximum allowed difference in Bland-Altman plot

Several other additions and improvements. See Update history.

February 14, 2017

New: Multiple frequency tables

New: Sample size calculation for McNemar test.

January 4, 2017

New: Case-control matching

New: Plot versus prevalence

Improved Recall dialog function.

Changed the methodology for calculation of the 95% confidence intervals for Positive and Negative Predictive Value to the "standard logit" method of: Mercaldo ND, Lau KF, Zhou XH (2007) Confidence intervals for predictive values with an emphasis to case-control studies. Statistics in Medicine 26:2170-2183. PubMed

Updated translations and language files.

See Update history for full list of updates.

  • user-friendly, fast and reliable statistical software
  • easy to learn
  • one edition includes all features
  • more than 220 statistical tests, procedures and graphs
    • reference software for ROC curve analysis...
    • method comparison and method evaluation including Bland & Altman plot, Passing & Bablok, and Deming regression, ...
    • reference intervals
    • meta-analysis
    • see complete list
  • free updates
  • available with an English, Chinese (simplified and traditional), French, German, Italian, Japanese, Korean, Polish, Portuguese (Brazilian), Russian and Spanish user-interface (help file and documentation in English)
  • compatible with all contemporary Windows desktop editions

Download free trial



MedCalc screenshot

Licensing options

Lifetime single-user license

For individuals

Allows 1 person to use the software

Not transferrable


No monthly or yearly fees

445 USD

Single-user subscription

For individuals or organizations

Allows 1 person to use the software

Not transferrable

Subscription based

Yearly fee

145 USD/year

Site license

For organizations

Allows unlimited use within your organization


Yearly fee

1780 USD/year

Network license

For organizations

Allows concurrent use by a limited number of users

Subscription-based - Yearly fee

Starting at 240 USD/year for 2 concurrent users

How to order

MedCalc manual

New paperback and Kindle e-reader editions cover version 17.9 of the software.

Paperback edition:

English, 345 pages, 29 USD.

Buy from Amazon US - UK - DE - FR - ES - IT - CA

Kindle e-reader edition:

English, 4.99 USD.

Buy from Amazon US - UK - DE - FR - ES - IT - CA