MedCalc - User-friendly statistical software

News and updates

April 16, 2017

Added "Root mean square" and "Logarithmic" methods for the calculation of the Coefficient of variation from duplicate measurements.

Added "Save differences" option in results window of Paired samples t-test and "Save residuals" option in results window of the Independent samples t-test.

Added test for Normal distribution of data in Normal plot

Added test for Normal distribution of differences in Paired samples t-test.

Added test for Normal distribution of residuals in Independent samples t-test, Regression, Multiple regression, One-way analysis of variance, Two-way analysis of variance, and Analysis of covariance.

April 3, 2017

New: sample size calculation for Bland-Altman plot.

New: option to draw lines for the Maximum allowed difference in Bland-Altman plot

Several other additions and improvements. See Update history.

February 14, 2017

New: Multiple frequency tables

New: Sample size calculation for McNemar test.

January 4, 2017

New: Case-control matching

New: Plot versus prevalence

Improved Recall dialog function.

Changed the methodology for calculation of the 95% confidence intervals for Positive and Negative Predictive Value to the "standard logit" method of: Mercaldo ND, Lau KF, Zhou XH (2007) Confidence intervals for predictive values with an emphasis to case-control studies. Statistics in Medicine 26:2170-2183. PubMed

Updated translations and language files.

April 11, 2016

New: Comparison of multiple methods.

Plot versus criterion values (ROC curve analysis): added plot of Cost and Misclassification-Cost Term (MCT) against criterion values.

Several improvements in meta-analysis.

January 6, 2016

Added the possibility to perform several independent samples and paired samples t-tests, Mann-Whitney tests and Wilcoxon tests in one single procedure, see Comparison of independent samples and Comparison of paired samples.

Added the possibility to save (or append) results, graphs and spreadsheet data to Word documents (docx). Use the new Save to Word button or the Ctrl+W keyboard shortcut.

October 22, 2015

New: Probit regression (Dose-Response analysis)

August 14, 2015

Added Funnel plots in meta-analysis.

Added a Generic inverse variance method for meta-analysis.

See Update history for full list of updates.

  • user-friendly, fast and reliable statistical software
  • easy to learn
  • one edition includes all features
  • more than 220 statistical tests, procedures and graphs
    • reference software for ROC curve analysis...
    • method comparison and method evaluation including Bland & Altman plot, Passing & Bablok, and Deming regression, ...
    • reference intervals
    • meta-analysis
    • see complete list
  • free updates
  • available with an English, Chinese (simplified and traditional), French, German, Italian, Japanese, Korean, Polish, Portuguese (Brazilian), Russian and Spanish user-interface (help file and documentation in English)
  • compatible with all contemporary Windows desktop editions

Download free trial



MedCalc screenshot

Licensing options

Lifetime single-user license

For individuals

Allows 1 person to use the software

Not transferrable


No monthly or yearly fees

445 USD

Single-user subscription

For individuals or organizations

Allows 1 person to use the software

Not transferrable

Subscription based

Yearly fee

145 USD/year

Site license

For organizations

Allows unlimited use within your organization


Yearly fee

1780 USD/year

Network license

For organizations

Allows concurrent use by a limited number of users

Subscription-based - Yearly fee

Starting at 240 USD/year for 2 concurrent users

How to order

MedCalc manual

New paperback and Kindle e-reader editions cover version 17.4 of the software.

Paperback edition:

English, 322 pages, 24 USD.

Buy from Amazon US - UK - DE - FR - ES - IT - NL - JP - BR - CA - MX - AU - IN

Kindle e-reader edition:

English, 3.99 USD.

Buy from Amazon US - UK - DE - FR - ES - IT - NL - JP - BR - CA - MX - AU - IN