Comparison of AUC of independent ROC curves
Use this calculator to compare the Area under the Curve (AUC) of two independent ROC curves.
Required input
Enter the Area under the Curve (AUC) and Standard Error (SE) for the two ROC curves.
Click the Test button to test the statistical significance of the difference between the two AUCs.
Interpretation
When the calculated P value is less than 0.05 (P<0.05), the conclusion is that the AUCs of the two ROC curves are significantly different.
Note that on MedCalc P-values are always two-sided (or two-tailed).
Methodology
MedCalc uses the method by Hanley & McNeil (1982 & 1983).
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Literature
- Hanley JA, McNeil BJ (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology, 143, 29-36.
- Hanley JA, McNeil BJ (1983) A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology, 148, 839-843.
How to cite this page
- MedCalc Software Ltd. Comparison of AUC of independent ROC curves. https://www.medcalc.org/en/calc/comparison_of_independentROCtest.php (Version 24.0; accessed October 11, 2026)
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See also
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