Skip to main content
Mail a PDF copy of this page to:
(Your email address will not be added to a mailing list)
Download our user-friendly MedCalc statistical software for your Windows desktop. Download

Other calculators ...

Free statistical calculators

Comparison of AUC of independent ROC curves

1st ROC curve

2nd ROC curve


This procedure allows to compare the Area under the Curve (AUC) of two independent ROC curves.

Required input

Enter the Area under the Curve (AUC) and Standard Error (SE) for the two ROC curves.

Click the Test button to test the statistical significance of the difference between the two AUCs.


When the calculated P value is less than 0.05 (P<0.05), the conclusion is that the AUCs of the two ROC curves are significantly different.

Note that on MedCalc P-values are always two-sided (or two-tailed).


MedCalc uses the method by Hanley & McNeil (1982 & 1983).


  • Hanley JA, McNeil BJ (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology, 143, 29-36.
  • Hanley JA, McNeil BJ (1983) A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology, 148, 839-843.

How to cite this page

  • MedCalc Software Ltd. Comparison of AUC of independent ROC curves. (Version 22.026; accessed June 24, 2024)